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Associate Scientist II, In Vitro Neuropharmacology

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Date: Aug 12, 2017

Location: Cambridge, MA, US

Company: Biogen

External Posting TitleAssociate Scientist II, In Vitro Neuropharmacology
Job DescriptionThe New Indications Research Unit group is seeking independent and motivated scientists to join a newly established research team focused on the rapid progression of novel therapeutics to humans for neurodegenerative, neurobehavioral and neuromuscular diseases. The successful candidate will be responsible for developing in vitro assays to perform compound screening, target validation and mechanism of action studies, in support of programs within the neuropharmacology therapeutic area.


• Develop cell-based and biochemical approaches to validate novel therapeutic targets and evaluate the activity and mechanism of action of drug candidates. This will require excellent assay troubleshooting skills and knowledge of analysis methodologies.

• Independently review the relevant literature to understand and propose the best methods that can be applied to the needs of the group.

• Provide strategic input and propose new initiatives for methods to validate novel targets and test therapeutics.

• Keep abreast of, and use, state-of-the-art technologies in target validation.

• Prepare, review and deliver scientific presentations, posters and reports for internal/external use.
LocationCambridge, MA, US
Job CategoryResearch
Requisition Number31830BR
• The candidate must have extensive experience with cell culture and working with a variety of cell lines.

• Is expected to have broad experience with cellular and biochemical techniques, including cell transfection/infection/electroporation, immunoblotting and immunoprecipitation, cell staining, ELISA.

• Is expected to be proficient at molecular biology techniques including RNA/DNA isolation, qPCR, siRNA, CRISPR.

• Experince with assay development and compound screening is a plus.

• Experince with primary neuronal cultures, brain dissections and background in neurobiology is a plus.

• The candidate must demonstrate a thorough knowledge of experimental design, underlying scientific principles, and the ability to independently and critically analyze results.

• Needs to have a demonstrated track record of leading support activities for multiple research projects, scientific and technical advancement, and co-authorship of peer-reviewed publications.

• The position requires excellent communication skills and ability to present data.

• Needs to be comfortable changing direction and priorities and learing new techniques.

• Willing to collaborate closely with researchers within the Neuropharmacology group as well as other departments.
EducationBS with at least 3 years or MS with at least one year of academic and/or industry experience
About BiogenCorporate Overview

Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Biogen is a pioneer in biotechnology and today the Company has the leading portfolio of medicines to treat multiple sclerosis (MS), has introduced the first and only approved treatment for spinal muscular atrophy, and is at the forefront of neurology research for conditions including Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS). Biogen also manufactures and commercializes biosimilars of advanced biologics. Our global organization of nearly 7,000 employees is committed to a single mission: making a meaningful difference in the lives of patients with few or no treatment options.

One of the pioneers in biotechnology, Biogen was founded in 1978 and today serves patients in nearly 90 countries. Our global headquarters and R&D operations are located in Cambridge, Massachusetts, with an international headquarters in Zug, Switzerland, world-class manufacturing facilities in Research Triangle Park, North Carolina, USA and Hillerod, Denmark, and affiliate locations around the world.

Our Science

We aspire to have the greatest impact on patients and science of any biotechnology company in the history of our industry. To us, that means creating novel medicines that benefit individuals and society, and bringing new scientific understanding to diseases for which there are no adequate treatments.

For nearly two decades Biogen has led in the research and development of new therapies to treat MS, including the most prescribed oral treatment in the world. Now our research is driving revolutionary new MS treatments with the goal of reversing or even repairing damage caused by the disease. We are now applying our neurological expertise to solve some of most challenging and complex diseases of the brain, including Alzheimer’s disease, Parkinson’s disease, and ALS. As we uncover new insights into human biology, Biogen is employing cutting-edge technologies to discover potential treatments for rare and genetic disorders.

Biogen is revolutionizing biologics manufacturing, developing the industry’s most advanced plants and processes. This expertise is used to produce both original innovative therapies and biosimilars that expand patient access to lower-cost medicines.

Our Corporate Citizenship

The same intellectual discipline and passion that drives our science is reflected in our corporate citizenship, environmental sustainability, and commitment to diversity and inclusion. As a company, we are focused on improving science education and limiting the impact of our company on the environment. In 2015, we became a carbon neutral company and ranked first place on Newsweek’s 2015 Green Rankings, and we are an industry leader on the Dow Jones Sustainability World Index. Biogen was named to Science’s list of Top Employers of 2015 and in 2017 received a perfect score of 100 for the fourth consecutive year on the Human Rights Campaign (HRC) Corporate Equality Index, which also named Biogen as one of its Best Places to Work.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Please be advised that all legitimate correspondence from a Biogen employee will come from "" email accounts.

Nearest Major Market: Cambridge
Nearest Secondary Market: Boston

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